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Causes:
1. Helicobacter Pylori positive ulcer disease: bacterial infection with
helicobacter pylori (Colonisation of the stomach mucosa is seen in 99%
of the stomach ulcers, in 75% of the duodenal ulcers and in around 50%
of health adults.
2. Genetic factors: Ulcers are seen more in
patients with blood type 0
3. Ulcer disease after the use of
nonsteroidal anti-inflammatory agents (NSAIDs) (risk is 4 times higher
of having ulcer disease, in combination with steroids even 12 times
higher)
4. acute stress induces ulcer disease
Syptoms:
- stomac pain after eating, sometimes also independent of eating
- bleeding
Therapie:
1. Tripel-Therapie. A proton pump inhibitor
(Omeprazol, Pantoprazol, Lansoprazol, Rabeprazol, Esomeprazol) in
combination with two antibiotics (metronidazole, tetracycline,
clarithromycin, amoxicillin) for seven days
3. Stopp the therapy with nonsteriodal
anti-inflammatory agents, in special in combination with steroids and
change to other drugs against pain or inflammation
First choice:
Proton pump inhibitors: Omeprazol,
Pantoprazol, Lansoprazol, Rabeprazol, Esomeprazol
Second choice:
H2-Blockers: Cimetidin, Ranitidin, Nizatidin,
Roxatidin, Famotidin
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